Indigion

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Generic Name:celecoxib (SEL e KOX ib)
Brand Name:Celebrex

The Indigo Platinum Mastercard is specifically designed for those with less than perfect credit. As an added plus, your monthly Indigo card payments are reported to all three major credit bureaus, which can help build a positive payment history. Adjective originating in and characteristic of a particular region or country; native (often followed by to): the plants indigenous to Canada.

Medically reviewed by Philip Thornton, DipPharm. Last updated on Dec 1, 2020.

What is Celebrex?

Celebrex (celecoxib) is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.

Celebrex is used to treat pain or inflammation caused by many conditions such as arthritis, ankylosing spondylitis, and menstrual pain.

Celebrex is used to treat juvenile rheumatoid arthritis in children who are at least 2 years old. It is also used in the treatment of hereditary polyps in the colon.

Warnings

Celebrex may cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults. You should not take this medicine if you already have bleeding in your stomach or intestines.

Celecoxib can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use Celebrex just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Before taking this medicine

You should not use Celebrex if you are allergic to celecoxib, or if you have:

  • an allergy to sulfa drugs; or

  • a history of asthma attack or severe allergic reaction after taking aspirin or an NSAID.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

  • a stomach ulcer, bleeding in your stomach or intestines;

  • heart disease, high blood pressure;

  • asthma;

  • bleeding problems;

  • liver or kidney disease; or

  • if you smoke or drink alcohol.

If you are pregnant, you should not take Celebrex unless your doctor tells you to. Taking a NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

How should I take Celebrex?

Take Celebrex exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides. Use the lowest dose that is effective in treating your condition.

Indigenous rising

You may take Celebrex with or without food.

If you cannot swallow a capsule whole, open it and sprinkle the medicine into a spoonful of applesauce. Swallow the mixture with water. You may save this applesauce mixture for later use in a refrigerator for up to 6 hours.

Store at room temperature away from moisture and heat.

Dosing information

Usual Adult Dose for Pain:

Acute pain: 400 mg initially, followed by 200 mg if needed on the first day. Then, 200 mg twice daily as needed.

Usual Adult Dose for Dysmenorrhea:

400 mg initially, followed by 200 mg if needed on the first day. Then, 200 mg twice daily as needed.

Usual Adult Dose for Osteoarthritis:

200 mg orally once daily or 100 mg orally twice daily.

Usual Adult Dose for Rheumatoid Arthritis:

100 to 200 mg orally twice daily.

Usual Adult Dose for Familial Adenomatous Polyposis:

400 mg orally twice daily with food.

Usual Adult Dose for Ankylosing Spondylitis:

200 mg orally once daily or 100 mg orally twice daily. If after 6 weeks of therapy no results are observed, a trial dose of 400 mg orally daily may be worthwhile. If no response is seen after 6 weeks, consideration should be given to alternate treatment options.

Usual Pediatric Dose for Juvenile Rheumatoid Arthritis:

2 years or older:
10 to less than or equal to 25 kg: 50 mg orally twice daily
Greater than 25 kg: 100 mg orally twice daily

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What to avoid

Avoid taking aspirin or other NSAIDs while you are taking Celebrex, unless your doctor tells you to.

Avoid drinking alcohol. It may increase your risk of stomach bleeding.

Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to celecoxib (such as aspirin, ibuprofen, ketoprofen, or naproxen).

Celebrex side effects

Get emergency medical help if you have signs of an allergic reaction to Celebrex (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath.

Stop using Celebrex and call your doctor at once if you have:

  • the first sign of any skin rash, no matter how mild;

  • heart problems - swelling, rapid weight gain, feeling short of breath;

  • signs of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;

  • liver problems -nausea, stomach pain (upper right side), itching, tiredness, dark urine, jaundice (yellowing of the skin or eyes);

  • kidney problems - little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or

  • low red blood cells (anemia) - pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.

Common Celebrex side effects may include:

  • stomach pain, heartburn, gas, diarrhea, constipation, nausea, vomiting;

  • swelling in your hands or feet;

  • dizziness; or

  • cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Celebrex?

Ask your doctor before using Celebrex if you take an antidepressant, steroid medicine, or medicine to treat or prevent blood clots. Taking certain medicines with an NSAID may increase your risk of a stomach ulcer or bleeding.

Many drugs can interact with celecoxib. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Celebrex drug interactions(more detail)

Frequently asked questions

More about Celebrex (celecoxib)

  • During Pregnancy or Breastfeeding

Consumer resources

Other brands
Elyxyb

Professional resources

Related treatment guides

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Celebrex only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Copyright 1996-2021 Cerner Multum, Inc. Version: 19.01.

Question: 'What are the religious / spiritual beliefs of Native Americans?'
Answer: Native Americans is a generic reference to people groups who lived in North and South America prior to the arrival of European explorers. Given the size of those two continents and their diverse landscapes, it is no surprise that Native American cultures varied drastically from group to group and from tribe to tribe. This means “Native American Religion” is an extremely broad category. The religious beliefs of modern Americans—and Asians, and Europeans, and Africans—span a wide range, and so do the spiritual traditions of Native Americans.
That being said, most Native American religions share a set of common features. Most important among these are a lack of distinction between the spiritual world and the natural world, the existence of some type of creative deity, and a general lack of objective, fixed principles. Few Native American religious ideas were considered absolutely unchangeable, and even fewer were codified in writing. As a result, historic spiritual beliefs in the Americas were diverse and extremely fluid.

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One common feature of many Native American spiritual traditions is a uniform view of reality. Christianity often speaks of a physical world and a spiritual world. At least for the sake of comparison, such a distinction does not exist in most Native American religions. The “world” of spirits and deities is the same “world” as that of nature and man, and whatever differences or separations may exist are frequently bridged.
Most Native American religions include some kind of divine Creator. In many cases, this is a single deity, often referred to as the Great Spirit. In some cases, this is a group of gods or a collection of spirits. And, in others, this spirit is more of an impersonal force than an actual, personal being. Because of this broad variation, individual Native American religions can be categorized as theistic, deistic, henotheistic, polytheistic, or even pantheistic.

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Native American religions are also typically devoid of objective rules or laws. This is not to suggest there are no moral principles in these spiritual traditions. However, such concepts are typically treated as guidelines or foundations and not as hard-and-fast regulations. Traditions vary from group to group, but Native American spirituality is typically much less rigid than systems such as Christianity, Buddhism, and Islam.
Written texts comparable to works such as the Bible, the Qur'an, or the Vedas do not exist in Native American religious history. Instead, oral tradition and personal teaching are strongly emphasized in Native American religious practice. The motivation for this is extremely practical. From the Native American perspective, the only way to learn traditions is to participate in them; there is little use for written texts.
The combination of fluid tenets, a lack of written scriptures, and wide variety of belief caused European explorers to badly misunderstand the spiritual traditions of Native Americans. The assumption of most colonizers was that native religion was shallow, simple, and unimportant. While Native Americans are, by comparison, far more comfortable combining their spiritual beliefs with those of other religions, their traditions are as deeply held and are considered just as meaningful as those of any other culture.
A particularly interesting feature of Native American religion is the recurrence of myths regarding a catastrophic, worldwide flood. As is the case with spiritual traditions around the world, several versions of a flood story can be found in Native American myths:
• Hopi folk tales speak of Tawa, the Sun Spirit, destroying the existing world (called the Third World) in a flood; a few good people survived by riding in reed boats (compare Genesis 6:6–8).
• An Ottawa story claims that a man angered the sea god, triggering a flood that covered the world. This man was saved by a goddess riding in a boat with pairs of surviving animals (compare Genesis 6:20).
• According to the Chippewa, a particularly powerful man killed the evil Great Serpent, triggering a mountain-covering flood (compare Genesis 7:19). People survived by boarding rafts and floating until the waters had subsided (compare Genesis 8:1).
• Cheyenne legends say a medicine man stretched a white buffalo skin between mountains to protect the people from a wrathful divine rain. When the primary god saw this and stopped the rain, the skin shrank and became the rainbow (compare Genesis 9:12–13).
• Salish myths feature many people having nightmares of a massive flood (compare Genesis 6:13). Those who believed the dreams banded together to build a huge raft made of canoes (compare Genesis 6:14), and only they survived the flood. Those who ignored the dreams drowned (compare Genesis 7:22–23). Afterwards, these survivors began to quarrel and scattered across the earth into different tribes (compare Genesis 11:1–9).

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These stories each echo aspects of the Bible’s description of the flood that destroyed the world of Noah’s time. The preservation of the basic story—seen in cultures across the world—is a point often brought up in discussions of mankind’s origins. If every human culture shares a common story, with several common details, there are good reasons to think that story has some basis in actual history.
Attempting to define Native American religion in any detail is futile. As with any other large collection of people groups, there are literally thousands of individual approaches to spirituality in Native American cultures. The concepts of fluidity, a unified spiritual and natural world, and a lack of written scriptures are shared across many of these traditions, but each is a completely independent worldview in and of itself.